Ariadna’s research is focused on the inflammatory regulation of miR-21 and fibrosis in the pathophysiology of endometriosis. This disorder is an estrogen-dependent inflammatory disease characterized by the presence of endometrial epithelial and stromal cells at ectopic locations. This can result in bleeding, inflammation, fibrosis and adhesion formation, primarily in the pelvic area causing pain and infertility in women. She researches the mechanisms by which IL-6 regulates mir-21 and how mir-21 affects TGF-β signaling. Ariadna also uses the mouse model of endometriosis to investigate mechanisms of fibrosis development.
- M. Ariadna Ochoa Bernal and Asgerally Fazleabas, 2020, “Physiologic Events of Embryo Implantation and Decidualization in Human and Non-Human Primates”, International Journal of Molecular Science.
Ariadna participated in the Girls Math & Science Day where she taught elementary school children basic concepts of genetics by performing different activities. Ariadna also volunteered during the Science Fair at the Research Center in Grand Rapids promoting STEM activities with GRPS high school students interested in a future career in science.